Synthesis and Evaluation of Novel E‐2‐(2‐Thienyl)‐ and Z‐2‐(3‐Thienyl)‐3‐Arylacrylonitriles as Antifungal and Anticancer Agents Artículo académico uri icon

Abstracto

  • AbstractA series of 3‐aryl‐2‐(2‐thienyl)acrylonitriles 7 and 3‐aryl‐2‐(3‐thienyl)acrylonitriles 8 were synthesized by the reaction of aromatic aldehydes 6 with 2‐ and 3‐thienylacetonitriles 4 and 5, and evaluated for antifungal and cytotoxic activities against a panel of opportunistic and pathogenic fungi and three different cancer cell lines, respectively.

autores

  • Quiroga, Jairo
  • Cobo, Débora
  • Insuasty, Braulio
  • Abonía, Rodrigo
  • Nogueras, Manuel
  • Cobo, Justo
  • Vasquez, Yelkaira
  • Gupta, Mahabir
  • Derita, Marcos
  • Zacchino, Susana

fecha de publicación

  • 2007

Número de páginas

  • 3

Página inicial

  • 603

Última página

  • 606

Volumen

  • 340

Cuestión

  • 11