ABSTRACT

The main objective of this study is to evaluate the dose response effects of the drug acetylsalicylic acid with caffeine in Phaseolus vulgaris plants, using a homemade methodology; the concentrations to which the plants were subjected are 18.3 mg / ml, 36.7 mg / ml, 55 mg / ml and 73.3 mg / ml of acetylsalicylic acid with caffeine; the tests were carried out in triplicate. As a result, it was observed that, when graphing the height measurements, as well as the changes in the leaves; the higher the drug concentration (73.3 mg / ml and 55 mg / ml), a more rapid and dramatic damage is observed in the structure, coloration, health and general appearance of the plant. On the other hand, they presented a mean difference of decrease between 5 and 6 cm for each day, while the plants with the two lowest exposures belonging to doses of 36.7 mg / ml and 18.3 mg / ml showed changes between 2 and 4 cm for each day of exposure to acetylsalicylic acid with caffeine. In conclusion, it was possible to evaluate the difference in the effects caused by different concentrations of acetylsalicylic acid with caffeine in the P. vulgaris species, coinciding with other studies in which positive effects of the drug were found at lower concentrations (2.1 mg / mL). It is recommended to carry out future studies including laboratory analysis of soil pH, percentage of fines, nutrients, among others.

AUTHORS
Karelis Barrios
Dídimo Cruz
Daniel Suárez